Electrostatic Force Triggering Elastic Condensation of Double-Stranded DNA for High-Performance One-Step Immunoassay
By Deng, Chunyan; Zhang, Manman; Liu, Chunyan; Deng, Honghua; Huang, Yan; Yang, Minghui; Xiang, Juan; Ren, Bin
Published in Analytical Chemistry
Abstract
Current strategies for high-performance immunoassay generally require a sandwich structure for signal amplification. This strategy is limited to multivalent antigens and complicates the detection scheme. Herein we demonstrate a class of simple one-step ultrasensitive immunoassay with the adoption of double-stranded DNA (dsDNA) as